Longstanding interoperability challenges prompted the creation of a number of public initiatives, all aimed at addressing the need for greater data flow, increased security, and trust and accountability between health entities. The Trusted Exchange Framework and Common Agreement (TEFCA)—led by the Office of the National Coordinator for Health Information Technology and born out of the 21st Century Cures Act—aims to foster a health ecosystem that allows for free data flow of electronic health information (EHI) between separate health information networks (HINs). TEFCA is composed of two parts: Trusted Exchange Framework (TEF) Common Agreement (CA) These work in tandem to establish the technical and legal requirements needed to support sharing of…